Pulmonary Metastatic Choriocarcinoma in a Patient with Ectopic Pregnancy

Authors

  • Fahimeh Nokhostin Gynecologist, Associated Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences Yazd, Iran
  • Mohammad Bashiri Zadeh MSc in Genetics , Department of Genetics, Elm va Honar University, Yazd, Iran
  • Razieh Dehghani Firouz Abadi Infertility Fellowship, Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Abstract:

Gestational trophoblastic tumor (GTT) most commonly follows a molar pregnancy. In fact, it can occur following gestational events such as induced or spontaneous abortion, ectopic pregnancy, and term pregnancy. In this study, we present the case of a patient with ectopic pregnancy who was treated with a single dose of methotrexate (MTX). The maximum titer of beta subunit of human chorionic gonadotropin (BHCG) was 402. Work up of occult metastatic GTT was carried out following MTX therapy, due to elevated BHCG titer. In the positron emission tomography (PET) scan, a 17-mm lesion was detected in the right lung and treated via thoracotomy resection and adjuvant chemotherapy. Within an 18-month follow up, the patient did not reveal any symptoms and the BHCG titer level did not increase. Findings of this study revealed that after MTX therapy for ectopic pregnancy patients need to be followed up. Moreover, lack of BHCG titer decline, even in low tittering after treatment with MTX, can be related to GTT tumors or inadequate treatment for ectopic pregnancy.

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Journal title

volume 5  issue 4

pages  1107- 1112

publication date 2017-10-01

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